Target：Cerberus

Fields：Wnt signaling pathway

Gene Name：CER1

Protein Name：Cerberus

Human Gene Id：9350

Human Swiss Prot No：O95813

Mouse Gene Id：12622

Mouse Swiss Prot No：O55233

Immunogen：The antiserum was produced against synthesized peptide derived from the Internal region of human CER1. AA range:91-140

Specificity：Cerberus Polyclonal Antibody detects endogenous levels of Cerberus protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CER1;DAND4;Cerberus;Cerberus-related protein;DAN domain family member 4

Observed Band(KD)：30kD

Background： This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity. [provided by RefSeq, Jul 2008],

Function：function:Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak.,PTM:N-glycosylated.,sequence caution:Translated as Ser.,similarity:Belongs to the DAN family.,similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain.,subunit:Forms monomers and predominantly dimers.,

Subcellular Location：Secreted .

Expression： Blood,PCR rescued clones,