Target：CEGT

Fields：Sphingolipid metabolism;Metabolic pathways

Gene Name：UGCG

Protein Name：Ceramide glucosyltransferase (EC 2.4.1.80) (GLCT-1) (Glucosylceramide synthase) (GCS) (UDP-glucose ceramide glucosyltransferase) (UDP-glucose:N-acylsphingosine D-glucosyltransferase)

Human Gene Id：7357

Human Swiss Prot No：Q16739

Mouse Swiss Prot No：O88693

Rat Swiss Prot No：Q9R0E0

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：CEGT Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：43kD

Background： This gene encodes an enzyme that catalyzes the first glycosylation step in the biosynthesis of glycosphingolipids, which are membrane components containing lipid and sugar moieties. The product of this reaction is glucosylceramide, which is the core structure of many glycosphingolipids. [provided by RefSeq, Dec 2014],

Function：catalytic activity:UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine.,function:Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a "flippase".,online information:GlycoGene database,pathway:Lipid metabolism; sphingolipid metabolism.,similarity:Belongs to the glycosyltransferase 2 family.,tissue specificity:Found in all tissues examined.,

Subcellular Location：Golgi apparatus membrane ; Multi-pass membrane protein .

Expression：Found in all tissues examined.