Target：CDY1

Gene Name：CDY1 CDY1A; CDY1B

Protein Name：Testis-specific chromodomain protein Y 1 (EC 2.3.1.48)

Human Gene Id：253175

Human Swiss Prot No：Q9Y6F8

Immunogen：Synthesized peptide derived from human protein . at AA range: 210-290

Specificity：CDY1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：59kD

Background： This gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. The human chromosome Y has two identical copies of this gene within a palindromic region; this record represents the more telomeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. Two protein isoforms are encoded by transcript variants of this gene. Additional transcript variants have been described, but their full-length nature has not been determined. [provided by

Function：catalytic activity:Acetyl-CoA + histone = CoA + acetylhistone.,function:Has histone acetyltransferase activity, with a preference for histone H4.,similarity:Contains 1 chromo domain.,tissue specificity:Testis specific.,

Subcellular Location：Nucleus .

Expression：Testis-specific. Detected in spermatids (at protein level).