Target:CDO
Fields:Hedgehog signaling pathway
Gene Name:CDON
Protein Name:Cell adhesion molecule-related/down-regulated by oncogenes
Human Gene Id:50937
Human Swiss Prot No:Q4KMG0
Mouse Swiss Prot No:Q32MD9
Immunogen:The antiserum was produced against synthesized peptide derived from human CDON. AA range:511-560
Specificity:CDO Polyclonal Antibody detects endogenous levels of CDO protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:CDON;CDO;Cell adhesion molecule-related/down-regulated by oncogenes
Molecular Weight(Da):139kD
Background: This gene encodes a cell surface receptor that is a member of the immunoglobulin superfamily. The encoded protein contains three fibronectin type III domains and five immunoglobulin-like C2-type domains. This protein is a member of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells and positively regulates myogenesis. [provided by RefSeq, Aug 2011],
Function:function:Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells.,PTM:N-glycosylated.,similarity:Contains 3 fibronectin type-III domains.,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Part of a complex that contains BOC, CDON, NEO1, cadherins and CTNNB1. Interacts with NTN3.,
Subcellular Location:Cell membrane ; Single-pass membrane protein .
Expression: Fetal brain,Fetal lung,Placenta,