Target：LUC7L2

Gene Name：LUC7L2

Protein Name：Putative RNA-binding protein Luc7-like 2

Human Gene Id：51631

Human Swiss Prot No：Q9Y383

Mouse Gene Id：192196

Mouse Swiss Prot No：Q7TNC4

Immunogen：The antiserum was produced against synthesized peptide derived from human LUC7L2. AA range:129-178

Specificity：LUC7L2 Polyclonal Antibody detects endogenous levels of LUC7L2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：LUC7L2;CGI-59;CGI-74;Putative RNA-binding protein Luc7-like 2

Observed Band(KD)：47kD

Background： This gene encodes a protein that contains a C2H2-type zinc finger, coiled-coil region and arginine, serine-rich (RS) domain. A similar protein in mouse interacts with sodium channel modifier 1, and the encoded protein may be involved in the recognition of non-consensus splice donor sites in association with the U1 snRNP spliceosomal subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011],

Function：function:May bind to RNA via its Arg/Ser-rich domain.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the Luc7 family.,similarity:Contains 1 C2H2-type zinc finger.,

Subcellular Location：Nucleus speckle . Nucleus, nucleoplasm . Colocalizes with SCNM1 and SNRNP70 in nuclear speckles. .

Expression： Brain,Epithelium,Skin,Uterus,