Target：Maf1

Gene Name：MAF1

Protein Name：Repressor of RNA polymerase III transcription MAF1 homolog

Human Gene Id：84232

Human Swiss Prot No：Q9H063

Mouse Gene Id：68877

Mouse Swiss Prot No：Q9D0U6

Rat Gene Id：315093

Rat Swiss Prot No：Q5XIH0

Immunogen：Synthesized peptide derived from Maf1 . at AA range: 110-190

Specificity：Maf1 Polyclonal Antibody detects endogenous levels of Maf1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：MAF1;Repressor of RNA polymerase III transcription MAF1 homolog

Molecular Weight(Da)：29kD

Background： This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression. [provided by RefSeq, Jul 2008],

Function：function:Mediator of diverse signals that repress RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.,similarity:Belongs to the MAF1 family.,subunit:Interacts with BRF2.,

Subcellular Location：Nucleus . Cytoplasm .

Expression： Brain,Epithelium,Lung,Uterus,