Target：CD69

Gene Name：CD69

Protein Name：Early activation antigen CD69

Human Gene Id：969

Human Swiss Prot No：Q07108

Mouse Gene Id：12515

Mouse Swiss Prot No：P37217

Immunogen：The antiserum was produced against synthesized peptide derived from the Internal region of human CD69. AA range:91-140

Specificity：CD69 Polyclonal Antibody detects endogenous levels of CD69 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CD69;CLEC2C;Early activation antigen CD69;Activation inducer molecule;AIM;BL-AC/P26;C-type lectin domain family 2 member C;EA1;Early T-cell activation antigen p60;GP32/28;Leukocyte surface antigen Leu-23;MLR-3;CD69

Observed Band(KD)：25kD

Background： This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. [provided by RefSeq, Aug 2011],

Function：developmental stage:Earliest inducible cell surface glycoprotein acquired during lymphoid activation.,function:Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.,induction:By antigens, mitogens or activators of PKC on the surface of T and B-lymphocytes. By interaction of IL-2 with the p75 IL-2R on the surface of NK cells.,online information:CD69,PTM:Constitutive Ser/Thr phosphorylation in both mature thymocytes and activated T-lymphocytes.,similarity:Contains 1 C-type lectin domain.,subunit:Homodimer; disulfide-linked.,tissue specificity:Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets.,

Subcellular Location：Membrane; Single-pass type II membrane protein.

Expression：Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets.