Target：CD58

Fields：Cell adhesion molecules;Epstein-Barr virus infection

Gene Name：CD58

Protein Name：Lymphocyte function-associated antigen 3

Human Gene Id：965

Human Swiss Prot No：P19256

Immunogen：The antiserum was produced against synthesized peptide derived from the Internal region of human CD58. AA range:31-80

Specificity：CD58 Polyclonal Antibody detects endogenous levels of CD58 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CD58;LFA3;Lymphocyte function-associated antigen 3;Ag3;Surface glycoprotein LFA-3;CD58

Observed Band(KD)：27kD

Background： This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009],

Function：function:Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,

Subcellular Location：[Isoform 1]: Cell membrane; Single-pass type I membrane protein.

Expression： Brain,Erythrocyte,