Target:CD56
Fields:Cell adhesion molecules;Prion disease
Gene Name:NCAM1
Protein Name:Neural cell adhesion molecule 1
Human Gene Id:4684
Human Swiss Prot No:P13591
Mouse Swiss Prot No:P13595
Immunogen:The antiserum was produced against synthesized peptide derived from the Internal region of human NCAM1. AA range:250-300
Specificity:CD56 Polyclonal Antibody detects endogenous levels of CD56 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. ELISA: 1:10000.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:NCAM1;NCAM;Neural cell adhesion molecule 1;N-CAM-1;NCAM-1;CD56
Observed Band(KD):94kD
Background: This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011],
Function:function:This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.,online information:N-CAM 140,online information:NCAM entry,similarity:Contains 2 fibronectin type-III domains.,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains.,
Subcellular Location:[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Cell membrane; Lipid-anchor, GPI-anchor.; [Isoform 4]: Cell membrane ; Lipid-anchor, GPI-anchor .; [Isoform 5]: Secreted.; [Isoform 6]: Secreted .
Expression: Brain,Brain cortex,Kidney,Ovary,Plasma,Skeletal muscle,Testis,