Target：CD32

Fields：Phagosome;Osteoclast differentiation;B cell receptor signaling pathway;Fc gamma R-mediated phagocytosis;Staphylococcus aureus infection;Tuberculosis;Measles

Gene Name：FCGR2B

Protein Name：Low affinity immunoglobulin gamma Fc region receptor II-b

Human Gene Id：2213

Human Swiss Prot No：P31994 

Immunogen：The antiserum was produced against synthesized peptide derived from human CD32. AA range:277-326

Specificity：CD32 Polyclonal Antibody detects endogenous levels of CD32 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：34kD

Background：The Fc fragment of IgG receptor IIb encoded by FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.