Target：CD315

Gene Name：PTGFRN

Protein Name：Prostaglandin F2 receptor negative regulator

Human Gene Id：5738

Human Swiss Prot No：Q9P2B2

Mouse Gene Id：19221

Mouse Swiss Prot No：Q9WV91

Rat Gene Id：29602

Rat Swiss Prot No：Q62786

Immunogen：The antiserum was produced against synthesized peptide derived from the Internal region of human PTGFRN. AA range:601-650

Specificity：CD315 Polyclonal Antibody detects endogenous levels of CD315 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：PTGFRN;CD9P1;EWIF;FPRP;KIAA1436;Prostaglandin F2 receptor negative regulator;CD9 partner 1;CD9P-1;Glu-Trp-Ile EWI motif-containing protein F;EWI-F;Prostaglandin F2-alpha receptor regulatory protein;Prostaglandin F2-alpha receptor-associated protein;CD315

Observed Band(KD)：98kD

Background：function:Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur.,sequence caution:Translated as Gln.,similarity:Contains 6 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with CD9 and CD81. Also seems to interacts with CD63, CD82 and CD151.,

Function：function:Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur.,sequence caution:Translated as Gln.,similarity:Contains 6 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with CD9 and CD81. Also seems to interacts with CD63, CD82 and CD151.,

Subcellular Location：Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Golgi apparatus, trans-Golgi network membrane ; Single-pass type I membrane protein .

Expression： Brain,Embryo,Epithelium,Heart,Liver,PCR rescued clones,