Target：CD2BP2

Gene Name：CD2BP2

Protein Name：CD2 antigen cytoplasmic tail-binding protein 2

Human Gene Id：10421

Human Swiss Prot No：O95400

Mouse Swiss Prot No：Q9CWK3

Immunogen：The antiserum was produced against synthesized peptide derived from human CD2 Tail-binding. AA range:101-150

Specificity：CD2BP2 Polyclonal Antibody detects endogenous levels of CD2BP2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CD2BP2;KIAA1178;CD2 antigen cytoplasmic tail-binding protein 2;CD2 cytoplasmic domain-binding protein 2;CD2 tail-binding protein 2

Observed Band(KD)：50kD

Background： This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008],

Function：similarity:Contains 1 GYF domain.,subunit:Binds the cytoplasmic domain of CD2 through the GYF domain.,

Subcellular Location：Cytoplasm. Nucleus. Predominantly nuclear.

Expression： Aorta,Brain,Epithelium,Liver,Lung,