Target：CD296

Gene Name：ART1

Protein Name：GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1

Human Gene Id：417

Human Swiss Prot No：P52961

Mouse Gene Id：11870

Mouse Swiss Prot No：Q60935

Immunogen：The antiserum was produced against synthesized peptide derived from the Internal region of human ART1. AA range:51-100

Specificity：CD296 Polyclonal Antibody detects endogenous levels of CD296 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：ART1;GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1;ADP-ribosyltransferase C2 and C3 toxin-like 1;ARTC1;Mono(ADP-ribosyl)transferase 1;CD296

Observed Band(KD)：37kD

Background： ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. The amino acid sequence consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins. This gene was previously designated ART2. [provided by RefSeq, Jul 2008],

Function：catalytic activity:NAD(+) + protein-L-arginine = nicotinamide + N(omega)-(ADP-D-ribosyl)-protein-L-arginine.,catalytic activity:NADP(+) + protein-L-arginine = nicotinamide + N(omega)-((2'-phospho-ADP)-D-ribosyl)-protein-L-arginine.,similarity:Belongs to the Arg-specific ADP-ribosyltransferase family.,

Subcellular Location：Sarcoplasmic reticulum membrane; Lipid-anchor, GPI-anchor.

Expression： Skeletal muscle,