Target：GNAO

Fields：Rap1 signaling pathway;Circadian entrainment;Retrograde endocannabinoid signaling;Glutamatergic synapse;Cholinergic synapse;Serotonergic synapse;GABAergic synapse;Dopaminergic synapse;Long-term depression;Estrogen signaling pathway;Melanogenesis;Oxytocin signaling pathway;Relaxin signaling pathway;Morphine addiction;Alcoholism;Chagas disease;Toxoplasmosis;Human cytomegalovirus infection;Human immunodeficiency virus 1 infection

Gene Name：GNAO1

Protein Name：Guanine nucleotide-binding protein G(o) subunit alpha

Human Gene Id：2775

Human Swiss Prot No：P09471

Mouse Swiss Prot No：P18872

Rat Swiss Prot No：P59215

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：GNAO Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：38kD

Background： The protein encoded by this gene represents the alpha subunit of the Go heterotrimeric G-protein signal-transducing complex. Defects in this gene are a cause of early-onset epileptic encephalopathy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015],

Function：function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear.,similarity:Belongs to the G-alpha family. G(i/o/t/z) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.,

Subcellular Location：Cell membrane . Membrane ; Lipid-anchor .

Expression： Brain,Endometrium,Myometrium,