Target:CD200
Gene Name:CD200
Protein Name:OX-2 membrane glycoprotein
Human Gene Id:4345
Human Swiss Prot No:P41217
Mouse Swiss Prot No:O54901
Rat Swiss Prot No:P04218
Immunogen:The antiserum was produced against synthesized peptide derived from the Internal region of human CD200. AA range:171-220
Specificity:CD200 Polyclonal Antibody detects endogenous levels of CD200 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:CD200;MOX1;MOX2;My033;OX-2 membrane glycoprotein;CD200
Observed Band(KD):31kD
Background: This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],
Function:function:Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with CD200R1.,
Subcellular Location:Cell membrane; Single-pass type I membrane protein.
Expression: Blood,Brain,Fetal brain,