Target：CD107a
Fields：Autophagy - animal;Lysosome;Phagosome;Tuberculosis
Gene Name：LAMP1
Protein Name：Lysosome-associated membrane glycoprotein 1
Human Gene Id：3916
Human Swiss Prot No：P11279
Mouse Swiss Prot No：P11438
Rat Gene Id：25328
Rat Swiss Prot No：P14562
Immunogen：The antiserum was produced against synthesized peptide derived from the Internal region of human LAMP1. AA range:211-260
Specificity：CD107a Polyclonal Antibody detects endogenous levels of CD107a protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：LAMP1;Lysosome-associated membrane glycoprotein 1;LAMP-1;Lysosome-associated membrane protein 1;CD107 antigen-like family member A;CD107a
Observed Band(KD)：120kD
Background： The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008],
Function：function:Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.,PTM:O- and N-glycosylated; some of the 18 N-linked glycans are polylactosaminoglycans.,similarity:Belongs to the LAMP family.,subcellular location:This protein shuttles between lysosomes, endosomes, and the plasma membrane.,
Subcellular Location：Cell membrane ; Single-pass type I membrane protein . Endosome membrane; Single-pass type I membrane protein . Lysosome membrane ; Single-pass type I membrane protein . Late endosome membrane ; Single-pass type I membrane protein . Cytolytic granule membrane ; Single-pass type I membrane protein . This protein shuttles between lysosomes, endosomes, and the plasma membrane (By similarity). Colocalizes with OSBPL1A at the late endosome (PubMed:16176980). .
Expression： Brain,Liver,Pancreas,Placenta,Plasma,Testis,
