Target：CD100

Fields：Axon guidance

Gene Name：SEMA4D

Protein Name：Semaphorin-4D

Human Gene Id：10507

Human Swiss Prot No：Q92854

Mouse Gene Id：20354

Mouse Swiss Prot No：O09126

Immunogen：The antiserum was produced against synthesized peptide derived from the N-terminal region of human SEMA4D. AA range:61-110

Specificity：CD100 Polyclonal Antibody detects endogenous levels of CD100 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SEMA4D;C9orf164;CD100;SEMAJ;Semaphorin-4D;A8;BB18;GR3;CD100

Observed Band(KD)：95kD

Background：function:May play a functional role in the immune system, as well as in the nervous system. Induces B-cells to aggregate and improves their viability in vitro.,similarity:Belongs to the semaphorin family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 PSI domain.,similarity:Contains 1 Sema domain.,subunit:Homodimer. Binds PLXNB1.,tissue specificity:Strongly expressed in skeletal muscle, peripheral blood lymphocytes, spleen, and thymus and also expressed at lower levels in testes, brain, kidney, small intestine, prostate, heart, placenta, lung and pancreas, but not in colon and liver.,

Function：function:May play a functional role in the immune system, as well as in the nervous system. Induces B-cells to aggregate and improves their viability in vitro.,similarity:Belongs to the semaphorin family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 PSI domain.,similarity:Contains 1 Sema domain.,subunit:Homodimer. Binds PLXNB1.,tissue specificity:Strongly expressed in skeletal muscle, peripheral blood lymphocytes, spleen, and thymus and also expressed at lower levels in testes, brain, kidney, small intestine, prostate, heart, placenta, lung and pancreas, but not in colon and liver.,

Subcellular Location：Cell membrane ; Single-pass type I membrane protein .

Expression：Strongly expressed in skeletal muscle, peripheral blood lymphocytes, spleen, and thymus and also expressed at lower levels in testes, brain, kidney, small intestine, prostate, heart, placenta, lung and pancreas, but not in colon and liver.