Target：CCS

Fields：Amyotrophic lateral sclerosis;Pathways of neurodegeneration - multiple diseases

Gene Name：CCS

Protein Name：Copper chaperone for superoxide dismutase

Human Gene Id：9973

Human Swiss Prot No：O14618

Mouse Swiss Prot No：Q9WU84

Immunogen：The antiserum was produced against synthesized peptide derived from human CCS. AA range:225-274

Specificity：CCS Polyclonal Antibody detects endogenous levels of CCS protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CCS;Copper chaperone for superoxide dismutase;Superoxide dismutase copper chaperone

Observed Band(KD)：32kD

Background： Copper chaperone for superoxide dismutase specifically delivers Cu to copper/zinc superoxide dismutase and may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor. [provided by RefSeq, Jul 2008],

Function：cofactor:Binds 1 zinc ion per subunit.,cofactor:Binds 2 copper ions per subunit.,function:Delivers copper to copper zinc superoxide dismutase (SOD1).,similarity:Contains 1 HMA domain.,similarity:In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.,subunit:Homodimer, and heterodimer with SOD1.,tissue specificity:Ubiquitous.,

Subcellular Location：Cytoplasm .

Expression：Ubiquitous.