Target：CCNK

Gene Name：CCNK CPR4

Protein Name：Cyclin-K

Human Gene Id：8812

Human Swiss Prot No：O75909

Mouse Swiss Prot No：O88874

Immunogen：Synthesized peptide derived from human protein . at AA range: 80-160

Specificity：CCNK Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：63kD

Background： The protein encoded by this gene is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin-dependent kinases (CDK) that phosphorylate the C-terminal domain (CTD) of the large subunit of RNA polymerase II. This gene product may play a dual role in regulating CDK and RNA polymerase II activities. [provided by RefSeq, Jul 2008],

Function：function:May play a role in transcriptional regulation. In vitro, is associated with a kinase activity toward both RNA polymerase II C-terminal domain and CDK2 (CAK).,similarity:Belongs to the cyclin family. Cyclin C subfamily.,subunit:Part of a cyclin-kinase pair in the RNA polymerase II holoenzyme. Binds to CDK9.,tissue specificity:Ubiquitously expressed. Highest levels in testis.,

Subcellular Location：Nucleus .

Expression：Widely expressed. Highest levels in testis.