Target：CCK
Fields：Neuroactive ligand-receptor interaction;Insulin secretion;Pancreatic secretion
Gene Name：CCK
Protein Name：Cholecystokinin
Human Gene Id：885
Human Swiss Prot No：P06307
Mouse Gene Id：12424
Mouse Swiss Prot No：P09240
Rat Gene Id：25298
Rat Swiss Prot No：P01355
Immunogen：The antiserum was produced against synthesized peptide derived from human CCK. AA range:46-95
Specificity：CCK Polyclonal Antibody detects endogenous levels of CCK protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：CCK;Cholecystokinin;CCK
Molecular Weight(Da)：13kD
Background： This gene encodes a member of the gastrin/cholecystokinin family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the peptide hormones cholecystokinin-8, -12, -33, and others. The encoded peptides have been shown to regulate gastric acid secretion and food intake. A sulfated form of cholecystokinin-8 may modulate neuronal activity in the brain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015],
Function：function:This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion.,online information:Cholecystokinin entry,PTM:The precursor is cleaved by proteases to produce a number of active cholecystokinins.,similarity:Belongs to the gastrin/cholecystokinin family.,subunit:Binds to CCK-A receptors in the pancreas and CCK-B receptors in the brain.,
Subcellular Location：Secreted.
Expression： Brain,Pancreas,
