Target：CCBE1

Gene Name：CCBE1 KIAA1983 UNQ1921/PRO4395

Protein Name：Collagen and calcium-binding EGF domain-containing protein 1 (Full of fluid protein homolog)

Human Gene Id：147372

Human Swiss Prot No：Q6UXH8

Mouse Swiss Prot No：Q3MI99

Immunogen：Synthesized peptide derived from human protein . at AA range: 120-200

Specificity：CCBE1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：44kD

Background： This gene is thought to function in extracellular matrix remodeling and migration. It is predominantly expressed in the ovary, but down regulated in ovarian cancer cell lines and primary carcinomas, suggesting its role as a tumour suppressor. Mutations in this gene have been associated with Hennekam lymphangiectasia-lymphedema syndrome, a generalized lymphatic dysplasia in humans. [provided by RefSeq, Mar 2010],

Function：function:Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis.,similarity:Belongs to the CCBE1 family.,similarity:Contains 1 EGF-like domain.,similarity:Contains 2 collagen-like domains.,tissue specificity:Not expressed in blood or lymphatic endothelial cells.,

Subcellular Location：Secreted .

Expression：Not expressed in blood or lymphatic endothelial cells.