Target：CBPB1

Fields：Pancreatic secretion;Protein digestion and absorption

Gene Name：CPB1 CPB PCPB

Protein Name：Carboxypeptidase B (EC 3.4.17.2) (Pancreas-specific protein) (PASP)

Human Gene Id：1360

Human Swiss Prot No：P15086

Rat Swiss Prot No：P19223

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：CBPB1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：45kD

Background： Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma. [provided by RefSeq, Jul 2008],

Function：catalytic activity:Preferential release of a C-terminal lysine or arginine amino acid.,cofactor:Binds 1 zinc ion per subunit.,similarity:Belongs to the peptidase M14 family.,tissue specificity:Pancreas.,

Subcellular Location：Secreted . Zymogen granule lumen .

Expression：Pancreas.