Target：Mash2

Gene Name：ASCL2

Protein Name：Achaete-scute homolog 2

Human Gene Id：430

Human Swiss Prot No：Q99929

Mouse Gene Id：17173

Mouse Swiss Prot No：O35885

Rat Gene Id：24209

Rat Swiss Prot No：P19360

Immunogen：Synthesized peptide derived from Mash2 . at AA range: 1-80

Specificity：Mash2 Polyclonal Antibody detects endogenous levels of Mash2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：ASCL2;BHLHA45;HASH2;Achaete-scute homolog 2;ASH-2;hASH2;Class A basic helix-loop-helix protein 45;bHLHa45;Mash2

Observed Band(KD)：25kD

Background：achaete-scute family bHLH transcription factor 2(ASCL2) Homo sapiens This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. [provided by RefSeq, Jul 2008],

Function：function:AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein.,tissue specificity:Expressed specifically in the extravillous trophoblasts of the developing placenta.,

Subcellular Location：Nucleus .

Expression：Expressed specifically in the extravillous trophoblasts of the developing placenta.