Target：Maspin

Fields：p53 signaling pathway;MicroRNAs in cancer

Gene Name：SERPINB5

Protein Name：Serpin B5

Human Gene Id：5268

Human Swiss Prot No：P36952

Mouse Gene Id：20724

Mouse Swiss Prot No：P70124

Rat Gene Id：116589

Rat Swiss Prot No：P70564

Immunogen：The antiserum was produced against synthesized peptide derived from human Serpin B5. AA range:91-140

Specificity：Maspin Polyclonal Antibody detects endogenous levels of Maspin protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SERPINB5;PI5;Serpin B5;Maspin;Peptidase inhibitor 5;PI-5

Observed Band(KD)：40kD

Background：function:Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Normal mammary epithelial cells.,

Function：function:Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Normal mammary epithelial cells.,

Subcellular Location：Secreted, extracellular space.

Expression：Normal mammary epithelial cells.