Target：RND3

Gene Name：RND3 ARHE RHO8 RHOE

Protein Name：Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3)

Human Gene Id：390

Human Swiss Prot No：P61587

Mouse Swiss Prot No：P61588

Rat Swiss Prot No：Q6SA80

Immunogen：Synthesized peptide derived from human protein . at AA range: 150-230

Specificity：RND3 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：26kD

Background： This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011],

Function：function:Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.,similarity:Belongs to the small GTPase superfamily. Rho family.,subunit:Binds ROCK1 (By similarity). Interacts with UBXD5.,tissue specificity:Ubiquitous.,

Subcellular Location：Golgi apparatus membrane; Peripheral membrane protein.

Expression：Ubiquitous.