Target：Casein Kinase I α1/1L

Fields：Wnt signaling pathway;Hedgehog signaling pathway;Alzheimer disease;Pathways of neurodegeneration - multiple diseases;Human papillomavirus infection;Breast cancer;Hepatocellular carcinoma;Gastric cancer

Gene Name：CSNK1A1/CSNK1A1L

Protein Name：Casein kinase I isoform alpha/Casein kinase I isoform alpha-like

Human Gene Id：122011/1452

Human Swiss Prot No：Q8N752/P48729

Rat Gene Id：113927

Rat Swiss Prot No：P97633

Immunogen：The antiserum was produced against synthesized peptide derived from human CKI-alpha1/L. AA range:141-190

Specificity：Casein Kinase I α1/1L Polyclonal Antibody detects endogenous levels of Casein Kinase I α1/1L protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CSNK1A1L;Casein kinase I isoform alpha-like;CKI-alpha-like;CK1;CSNK1A1;Casein kinase I isoform alpha;CKI-alpha;CK1

Observed Band(KD)：30kD

Background：catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,

Function：catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,

Subcellular Location：Cytoplasm .

Expression： Testis,