Target：CANT1
Fields：Purine metabolism;Pyrimidine metabolism;Metabolic pathways;Nucleotide metabolism
Gene Name：CANT1 SHAPY
Protein Name：Soluble calcium-activated nucleotidase 1 (SCAN-1) (EC 3.6.1.6) (Apyrase homolog) (Putative MAPK-activating protein PM09) (Putative NF-kappa-B-activating protein 107)
Human Gene Id：124583
Human Swiss Prot No：Q8WVQ1
Mouse Swiss Prot No：Q8VCF1
Rat Swiss Prot No：Q8K4Y7
Immunogen：Synthesized peptide derived from part region of human protein
Specificity：CANT1 Polyclonal Antibody detects endogenous levels of protein.
Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500-2000 ELISA 1:5000-20000
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD)：44kD
Background：calcium activated nucleotidase 1(CANT1) Homo sapiens This protein encoded by this gene belongs to the apyrase family. It functions as a calcium-dependent nucleotidase with a preference for UDP. Mutations in this gene are associated with Desbuquois dysplasia with hand anomalies. Alternatively spliced transcript variants have been noted for this gene.[provided by RefSeq, Mar 2010],
Function：catalytic activity:A nucleoside diphosphate + H(2)O = a nucleotide + phosphate.,cofactor:Calcium.,function:Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP.,miscellaneous:Not inhibited by azide.,PTM:N-glycosylated.,similarity:Belongs to the apyrase family.,subcellular location:Processed form: Secreted.,subunit:Monomer.,tissue specificity:Widely expressed.,
Subcellular Location：Endoplasmic reticulum membrane ; Single-pass type II membrane protein . Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein . Cell membrane . Processed form: Secreted.
Expression：Widely expressed.
