Target：CANB1

Fields：MAPK signaling pathway;Calcium signaling pathway;cGMP-PKG signaling pathway;Oocyte meiosis;Cellular senescence;Wnt signaling pathway;Axon guidance;VEGF signaling pathway;Osteoclast differentiation;C-type lectin receptor signaling pathway;Natural killer cell mediated cytotoxicity;Th1 and Th2 cell differentiation;Th17 cell differentiation;T cell receptor signaling pathway;B cell receptor signaling pathway;Long-term potentiation;Glutamatergic synapse;Oxytocin signaling pathway;Glucagon signaling pathway;Renin secretion;Alzheimer disease;Amyotrophic lateral sclerosis;Prion disease;Pathways of neurodegeneration - multiple diseases;Amphetamine addiction;Tuberculosis;Human cytomegalovirus infection;Human T-cell leukemia virus 1 infection;Kaposi sarcoma-associated herpesvirus infection;Human immunodeficiency virus 1 infection;PD-L1 expression and PD-1 checkpoint pathway in cancer;Lipid and atherosclerosis

Gene Name：PPP3R1 CNA2 CNB

Protein Name：Calcineurin subunit B type 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1)

Human Gene Id：5534

Human Swiss Prot No：P63098

Mouse Swiss Prot No：Q63810

Rat Swiss Prot No：P63100

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：CANB1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：18kD

Background：function:Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.,miscellaneous:This protein has four functional calcium-binding sites.,similarity:Belongs to the calcineurin regulatory subunit family.,similarity:Contains 4 EF-hand domains.,subunit:Composed of a catalytic subunit (A) and a regulatory subunit (B).,

Function：function:Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.,miscellaneous:This protein has four functional calcium-binding sites.,similarity:Belongs to the calcineurin regulatory subunit family.,similarity:Contains 4 EF-hand domains.,subunit:Composed of a catalytic subunit (A) and a regulatory subunit (B).,

Subcellular Location：Cytoplasm, cytosol . Cell membrane . Cell membrane, sarcolemma . Cell membrane ; Lipid-anchor . Translocates from the cytosol to the sarcolemma in a CIB1-dependent manner during cardiomyocyte hypertrophy. .

Expression： Blood,Fetal brain cortex,