Target：Cadherin-22

Gene Name：CDH22

Protein Name：Cadherin-22

Human Gene Id：64405

Human Swiss Prot No：Q9UJ99

Mouse Swiss Prot No：Q9WTP5

Rat Gene Id：29182

Rat Swiss Prot No：Q63315

Immunogen：The antiserum was produced against synthesized peptide derived from human CDH22. AA range:111-160

Specificity：Cadherin-22 Polyclonal Antibody detects endogenous levels of Cadherin-22 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CDH22;C20orf25;Cadherin-22;Pituitary and brain cadherin;PB-cadherin

Observed Band(KD)：84kD

Background： This gene is a member of the cadherin superfamily. The gene product is composed of five cadherin repeat domains and a cytoplasmic tail similar to the highly conserved cytoplasmic region of classical cadherins. Expressed predominantly in the brain, this putative calcium-dependent cell adhesion protein may play an important role in morphogenesis and tissue formation in neural and non-neural cells during development and maintenance of the brain and neuroendocrine organs. [provided by RefSeq, Jul 2008],

Function：function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. PB-cadherins may have a role in the morphological organization of pituitary gland and brain tissues.,similarity:Contains 5 cadherin domains.,

Subcellular Location：Cell membrane ; Single-pass type I membrane protein .

Expression： Brain,Testis,