Target:Cadherin-19
Gene Name:CDH19
Protein Name:Cadherin-19
Human Gene Id:28513
Human Swiss Prot No:Q9H159
Immunogen:The antiserum was produced against synthesized peptide derived from human CDH19. AA range:371-420
Specificity:Cadherin-19 Polyclonal Antibody detects endogenous levels of Cadherin-19 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:CDH19;CDH7L2;Cadherin-19
Observed Band(KD):87kD
Background: This gene is one of three related type II cadherin genes situated in a cluster on chromosome 18. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein containing five extracellular cadherin repeats. Loss of cadherins may be associated with cancer formation. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Aug 2012],
Function:function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.,similarity:Contains 5 cadherin domains.,tissue specificity:Expressed in many tissues, with the exception of uterus.,
Subcellular Location:Cell membrane; Single-pass type I membrane protein.
Expression:Expressed in many tissues, with the exception of uterus.