Target：Abin-2

Gene Name：TNIP2 ABIN2 FLIP1

Protein Name：TNFAIP3-interacting protein 2 (A20-binding inhibitor of NF-kappa-B activation 2) (ABIN-2) (Fetal liver LKB1-interacting protein)

Human Gene Id：79155

Human Swiss Prot No：Q8NFZ5

Mouse Gene Id：231130

Mouse Swiss Prot No：Q99JG7

Immunogen：Synthetic peptide from human protein at AA range: 61-110

Specificity：The antibody detects endogenous Abin-2

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：TNFAIP3-interacting protein 2 (A20-binding inhibitor of NF-kappa-B activation 2;ABIN-2;Fetal liver LKB1-interacting protein)

Background： This gene encodes a protein which acts as an inhibitor of NFkappaB activation. The encoded protein is also involved in MAP/ERK signaling pathway in specific cell types. It may be involved in apoptosis of endothelial cells. Alternative splicing results in multiple transcript variants. A pseudogene related to this gene is located on the X chromosome.[provided by RefSeq, May 2014],

Function：function:Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation.,subunit:Interacts with STK11, TNFAIP3, IKBKG, NFKB1, MAP3K8 and RIPK1.,tissue specificity:Ubiquitously expressed in all tissues examined.,

Subcellular Location：Cytoplasm . Nucleus .

Expression：Ubiquitously expressed in all tissues examined.