Target：CA VA

Fields：Nitrogen metabolism;Metabolic pathways

Gene Name：CA5A

Protein Name：Carbonic anhydrase 5A mitochondrial

Human Gene Id：763

Human Swiss Prot No：P35218

Mouse Swiss Prot No：P23589

Immunogen：The antiserum was produced against synthesized peptide derived from human CA5A. AA range:171-220

Specificity：CA VA Polyclonal Antibody detects endogenous levels of CA VA protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CA5A;CA5;Carbonic anhydrase 5A; mitochondrial;Carbonate dehydratase VA;Carbonic anhydrase VA;CA-VA

Observed Band(KD)：35kD

Background： Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VA is localized in the mitochondria and expressed primarily in the liver. It may play an important role in ureagenesis and gluconeogenesis. CA5A gene maps to chromosome 16q24.3 and an unprocessed pseudogene has been assigned to 16p12-p11.2. [provided by RefSeq, Jul 2008],

Function：catalytic activity:H(2)CO(3) = CO(2) + H(2)O.,cofactor:Zinc.,function:Reversible hydration of carbon dioxide.,similarity:Belongs to the alpha-carbonic anhydrase family.,

Subcellular Location：Mitochondrion .

Expression： Liver,Umbilical cord,