Target：C/EBP ζ

Gene Name：CEBPZ

Protein Name：CCAAT/enhancer-binding protein zeta

Human Gene Id：10153

Human Swiss Prot No：Q03701

Mouse Swiss Prot No：P53569

Immunogen：The antiserum was produced against synthesized peptide derived from human CEBPZ. AA range:1-50

Specificity：C/EBP ζ Polyclonal Antibody detects endogenous levels of C/EBP ζ protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CEBPZ;CBF2;CCAAT/enhancer-binding protein zeta;CCAAT-box-binding transcription factor;CBF;CCAAT-binding factor

Observed Band(KD)：120kD

Background： This gene belongs to the CEBP family. The encoded protein plays a role in cellular response to environmental stimuli through a transcriptional process that involves heat shock factors, conserved DNA elements (heat shock elements or HSEs) and CCAAT boxes. The protein acts as a DNA-binding transcriptional activator and regulates the heat-shock protein 70 (HSP70) promoter in a CCAAT-dependent manner. The protein is also involved in cell growth and differentiation, particularly, hematopoietic differentiation. Methylation of the promoter of this gene or mutations within the gene may be correlated with occurance of acute myeloid leukemia (AML). [provided by RefSeq, Jun 2016],

Function：function:Stimulates transcription from the HSP70 promoter.,similarity:Belongs to the CBF/MAK21 family.,

Subcellular Location：Nucleus.

Expression： Epithelium,Testis,