Target：BS69

Gene Name：ZMYND11

Protein Name：Zinc finger MYND domain-containing protein 11

Human Gene Id：10771

Human Swiss Prot No：Q15326

Mouse Swiss Prot No：Q8R5C8

Immunogen：The antiserum was produced against synthesized peptide derived from human ZMY11. AA range:111-160

Specificity：BS69 Polyclonal Antibody detects endogenous levels of BS69 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：ZMYND11;BS69;Zinc finger MYND domain-containing protein 11;Adenovirus 5 E1A-binding protein;Protein BS69

Molecular Weight(Da)：66kD

Background： The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

Function：function:Binds to the transactivation domain of the adenovirus type 5 E1A 32 kDa protein (289R) and inhibits its transactivating activity. May act as tumor suppressor through suppression of adenovirus replication.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 bromo domain.,similarity:Contains 1 MYND-type zinc finger.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 1 PWWP domain.,

Subcellular Location：Nucleus . Chromosome . Associates with chromatin and mitotic chromosomes. .

Expression：Ubiquitous.