Target：BRAF35

Gene Name：HMG20B

Protein Name：SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

Human Gene Id：10362

Human Swiss Prot No：Q9P0W2

Mouse Swiss Prot No：Q9Z104

Immunogen：The antiserum was produced against synthesized peptide derived from human HMG20B. AA range:1-50

Specificity：BRAF35 Polyclonal Antibody detects endogenous levels of BRAF35 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：HMG20B;BRAF35;HMGX2;HMGXB2;SMARCE1R;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related;SMARCE1-related protein;BRCA2-associated factor 35;HMG box-containing protein 20B;HMG domain-

Observed Band(KD)：36kD

Background：function:Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.,sequence caution:Translation N-terminally extended.,similarity:Contains 1 HMG box DNA-binding domain.,subcellular location:Localized to condensed chromosomes in mitosis in conjunction with BRCA2.,subunit:Component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, AOF2/LSD1, RCOR1/CoREST and PHF21A/BHC80. The BHC complex may also contain ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I. Interacts with the BRCA2 tumor suppressor protein.,tissue specificity:Ubiquitously expressed in adult tissues.,

Function：function:Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.,sequence caution:Translation N-terminally extended.,similarity:Contains 1 HMG box DNA-binding domain.,subcellular location:Localized to condensed chromosomes in mitosis in conjunction with BRCA2.,subunit:Component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, AOF2/LSD1, RCOR1/CoREST and PHF21A/BHC80. The BHC complex may also contain ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I. Interacts with the BRCA2 tumor suppressor protein.,tissue specificity:Ubiquitously expressed in adult tissues.,

Subcellular Location：Nucleus. Chromosome. Localized to condensed chromosomes in mitosis in conjunction with BRCA2.

Expression：Ubiquitously expressed in adult tissues.