Target:BACH2
Gene Name:BACH2
Protein Name:Transcription regulator protein BACH2 (BTB and CNC homolog 2)
Human Gene Id:60468
Human Swiss Prot No:Q9BYV9
Mouse Swiss Prot No:P97303
Immunogen:Synthesized peptide derived from human protein . at AA range: 250-330
Specificity:BACH2 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):115kD
Background:function:Transcriptional regulator that acts as repressor or activator. Binds to Maf recognition elements (MARE). Play important roles in coordinating transcription activation and repression by MAFK.,similarity:Belongs to the bZIP family. CNC subfamily.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 1 bZIP domain.,subunit:Heterodimer of BACH2 and Maf-related transcription factors.,tissue specificity:B-cell specific.,
Function:function:Transcriptional regulator that acts as repressor or activator. Binds to Maf recognition elements (MARE). Play important roles in coordinating transcription activation and repression by MAFK.,similarity:Belongs to the bZIP family. CNC subfamily.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 1 bZIP domain.,subunit:Heterodimer of BACH2 and Maf-related transcription factors.,tissue specificity:B-cell specific.,
Subcellular Location:Cytoplasm . Nucleus . Nucleocytoplasmic shuttling is controlled by phosphorylation. .
Expression:B-cell specific.