Target：B4GN2
Gene Name：B4GALNT2 GALGT2
Protein Name：Beta-1,4 N-acetylgalactosaminyltransferase 2 (EC 2.4.1.-) (Sd(a) beta-1,4-GalNAc transferase) (UDP-GalNAc:Neu5Aca2-3Galb-R b1,4-N-acetylgalactosaminyltransferase)
Human Gene Id：124872
Human Swiss Prot No：Q8NHY0
Mouse Swiss Prot No：Q09199
Immunogen：Synthesized peptide derived from part region of human protein
Specificity：B4GN2 Polyclonal Antibody detects endogenous levels of protein.
Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500-2000 ELISA 1:5000-20000
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD)：62kD
Background：beta-1,4-N-acetyl-galactosaminyltransferase 2(B4GALNT2) Homo sapiens B4GALNT2 catalyzes the last step in the biosynthesis of the human Sd(a) antigen through the addition of an N-acetylgalactosamine residue via a beta-1,4 linkage to a subterminal galactose residue substituted with an alpha-2,3-linked sialic acid. B4GALNT2 also catalyzes the last step in the biosynthesis of the Cad antigen (Montiel et al., 2003 [PubMed 12678917]).[supplied by OMIM, Mar 2008],
Function：function:Involved in the synthesis of the Sd(a) antigen (Sia-alpha2,3-[GalNAc-beta1,4]Gal-beta1,4-GlcNAc), a carbohydrate determinant expressed on erythrocytes, the colonic mucosa and other tissues. Transfers a beta-1,4-linked GalNAc to the galactose residue of an alpha-2,3-sialylated chain.,online information:Beta-1,4 N-acetylgalactosaminyltransferase 2,online information:GlycoGene database,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 2 family.,tissue specificity:Widely expressed. Highly expressed in colon and to a lesser extent in kidney, stomach, ileum and rectum.,
Subcellular Location：Golgi apparatus membrane ; Single-pass type II membrane protein .
Expression：Widely expressed. Highly expressed in colon and to a lesser extent in kidney, stomach, ileum and rectum.
