Target：GKN2

Gene Name：GKN2 BLOT GDDR TFIZ1 UNQ465/PRO813

Protein Name：Gastrokine-2 (Blottin) (Down-regulated in gastric cancer) (Trefoil factor interactions(z) 1)

Human Gene Id：200504

Human Swiss Prot No：Q86XP6

Mouse Swiss Prot No：Q9CQS6

Rat Swiss Prot No：Q29TV8

Immunogen：Synthesized peptide derived from human protein . at AA range: 30-110

Specificity：GKN2 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：20kD

Background： The secretory protein encoded by this gene is produced in gastric surface mucous cells, where it can bind trefoil factor family peptide 1 or gastrokine-1. This gene may be a tumor suppressor gene, as its expression is markedly decreased in gastric cancer tissues. The encoded protein interacts with gastrokine-1 and regulates homeostasis of the gastric mucosa. [provided by RefSeq, Dec 2015],

Function：similarity:Contains 1 BRICHOS domain.,subunit:Interacts with TFF2 (By similarity). Heterodimer with TFF1; disulfide linked.,tissue specificity:Expressed in gastric mucosa.,

Subcellular Location：Secreted.

Expression：Expressed in gastric mucosa.