Target：MEF-2
Fields：cGMP-PKG signaling pathway;Apelin signaling pathway
Gene Name：MEF2B
Protein Name：Myocyte-specific enhancer factor 2B
Human Gene Id：4207
Human Swiss Prot No：Q02080
Mouse Swiss Prot No：O55087
Immunogen：The antiserum was produced against synthesized peptide derived from human MEF2B. AA range:51-100
Specificity：MEF-2B Polyclonal Antibody detects endogenous levels of MEF-2B protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：MEF2B;XMEF2;Myocyte-specific enhancer factor 2B;RSRFR2;Serum response factor-like protein 2
Observed Band(KD)：38kD
Background： This gene represents numerous read-through transcripts that span GeneID:729991 and 100271849. Many read-through transcripts are predicted to be nonsense-mediated decay (NMD) candidates, and are thought to be non-coding. Some transcripts are predicted to be capable of translation reinitiation at a downstream AUG, resulting in expression of at least one isoform of myocyte enhancer factor 2B (MEF2B) from this read-through locus. At least one additional MEF2B variant and isoform can be expressed from a downstream promoter, and is annotated on GeneID:100271849. [provided by RefSeq, Oct 2010],
Function：function:Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription.,similarity:Belongs to the MEF2 family.,similarity:Contains 1 MADS-box domain.,similarity:Contains 1 Mef2-type DNA-binding domain.,subunit:Interacts with HDAC7 (By similarity). Heterodimer. Interacts with HDAC9.,tissue specificity:Expressed in skeletal and cardiac muscle and brain.,
Subcellular Location：Nucleus.
Expression：Expressed in skeletal and cardiac muscle and brain.
