Target：B2L14

Gene Name：BCL2L14 BCLG

Protein Name：Apoptosis facilitator Bcl-2-like protein 14 (Bcl2-L-14) (Apoptosis regulator Bcl-G)

Human Gene Id：79370

Human Swiss Prot No：Q9BZR8

Mouse Swiss Prot No：Q9CPT0

Rat Swiss Prot No：Q6AYK4

Immunogen：Synthesized peptide derived from human protein . at AA range: 200-280

Specificity：B2L14 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：35kD

Background： The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce apoptosis in cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene. [provided by RefSeq, May 2009],

Function：function:May play a role in apoptosis.,similarity:Belongs to the Bcl-2 family.,subcellular location:Diffusely distributed throughout the cytosol.,subcellular location:Predominantly localized to cytosolic organelles.,tissue specificity:Isoform 1 is widely expressed and isoform 2 is testis-specific.,

Subcellular Location：Cytoplasm .; [Isoform 1]: Cytoplasm, cytosol. Diffusely distributed throughout the cytosol.; [Isoform 2]: Endomembrane system. Predominantly localized to cytosolic organelles.

Expression：Isoform 1 is widely expressed. Isoform 2 is testis-specific.