Target：ATS20

Gene Name：ADAMTS20

Protein Name：A disintegrin and metalloproteinase with thrombospondin motifs 20 (ADAM-TS 20) (ADAM-TS20) (ADAMTS-20) (EC 3.4.24.-)

Human Gene Id：80070

Human Swiss Prot No：P59510

Mouse Swiss Prot No：P59511

Immunogen：Synthesized peptide derived from human protein . at AA range: 190-270

Specificity：ATS20 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：210kD

Background： The protein encoded by this gene is a member of the ADAMTS family of zinc-dependent proteases. The encoded protein has a signal peptide that is cleaved to release the mature peptide, which is secreted and found in the extracellular matrix. This protein may be involved in tissue remodeling. [provided by RefSeq, Sep 2011],

Function：cofactor:Binds 1 zinc ion per subunit.,function:May play a role in tissue-remodeling process occurring in both normal and pathological conditions.,PTM:The precursor is cleaved by a furin endopeptidase.,similarity:Contains 1 disintegrin domain.,similarity:Contains 1 GON domain.,similarity:Contains 1 peptidase M12B domain.,similarity:Contains 15 TSP type-1 domains.,tissue specificity:Very sparingly expressed, although is detected at low levels in testis, prostate, ovary, heart, placenta, lung and pancreas. Overexpressed in several brain, colon and breast carcinomas.,

Subcellular Location：Secreted, extracellular space, extracellular matrix .

Expression：Very sparingly expressed, although is detected at low levels in testis, prostate, ovary, heart, placenta, lung and pancreas. Overexpressed in several brain, colon and breast carcinomas.