Target：Blr1

Fields：Cytokine-cytokine receptor interaction;Viral protein interaction with cytokine and cytokine receptor;Chemokine signaling pathway

Gene Name：CXCR5

Protein Name：C-X-C chemokine receptor type 5

Human Gene Id：643

Human Swiss Prot No：P32302

Mouse Swiss Prot No：Q04683

Immunogen：The antiserum was produced against synthesized peptide derived from the N-terminal region of human CXCR5. AA range:1-50

Specificity：Blr1 Polyclonal Antibody detects endogenous levels of Blr1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CXCR5;BLR1;MDR15;C-X-C chemokine receptor type 5;CXC-R5;CXCR-5;Burkitt lymphoma receptor 1;Monocyte-derived receptor 15;MDR-15;CD185

Observed Band(KD)：42kD

Background：C-X-C motif chemokine receptor 5(CXCR5) Homo sapiens This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011],

Function：function:Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.,online information:CXC chemokine receptors entry,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expression in mature B-cells and Burkitt lymphoma cells.,

Subcellular Location：Cell membrane; Multi-pass membrane protein.

Expression：Expression in mature B-cells and Burkitt lymphoma cells.