Target:ARL11
Gene Name:ARL11 ARLTS1
Protein Name:ADP-ribosylation factor-like protein 11 (ADP-ribosylation factor-like tumor suppressor protein 1)
Human Gene Id:115761
Human Swiss Prot No:Q969Q4
Mouse Swiss Prot No:Q6P3A9
Rat Swiss Prot No:Q5BK71
Immunogen:Synthesized peptide derived from human protein . at AA range: 140-220
Specificity:ARL11 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):21kD
Background: This gene encodes a tumor suppressor related to the ADP-ribosylation factor (ARF) family of proteins. The encoded protein may play a role in apoptosis in a caspase-dependent manner. Polymorphisms in this gene have been associated with some familial cancers. [provided by RefSeq, May 2010],
Function:disease:Defects in ARL11 may be a cause of susceptibility to chronic lymphocytic leukemia (CLL) [MIM:151400].,function:May play a role in apoptosis. May act as a tumor suppressor.,similarity:Belongs to the small GTPase superfamily. Arf family.,tissue specificity:Expressed in lung and leukocytes.,
Subcellular Location:intracellular,
Expression:Expressed in lung and leukocytes.