Target：ANX13
Gene Name：ANXA13 ANX13
Protein Name：Annexin A13 (Annexin XIII) (Annexin-13) (Intestine-specific annexin) (ISA)
Human Gene Id：312
Human Swiss Prot No：P27216
Mouse Swiss Prot No：Q99JG3
Immunogen：Synthesized peptide derived from part region of human protein
Specificity：ANX13 Polyclonal Antibody detects endogenous levels of protein.
Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500-2000 ELISA 1:5000-20000
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD)：34kD
Background： This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. The specific function of this gene has not yet been determined; however, it is associated with the plasma membrane of undifferentiated, proliferating endothelial cells and differentiated villus enterocytes. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
Function：domain:A pair of annexin repeats may form one binding site for calcium and phospholipid.,similarity:Belongs to the annexin family.,similarity:Contains 4 annexin repeats.,subcellular location:Associated with the plasma membrane of undifferentiated, proliferating crypt epithelial cells as well as differentiated villus enterocytes.,tissue specificity:Gut specific.,
Subcellular Location：Apical cell membrane . Cell membrane ; Lipid-anchor . Cytoplasmic vesicle . Myristoylation anchors the protein to the membrane, but the protein displays also calcium-dependent, reversible binding to lipid membranes (PubMed:30610115). Associated with the plasma membrane of undifferentiated, proliferating crypt epithelial cells as well as differentiated villus enterocytes (PubMed:1530946). .
Expression：Detected in epithelial cells in colon and jejunum (at protein level). Detected in epithelial cells in jejunum.
