Target:GK2
Fields:Glycerolipid metabolism;Metabolic pathways;PPAR signaling pathway
Gene Name:GK2
Protein Name:Glycerol kinase 2
Human Gene Id:2712
Human Swiss Prot No:Q14410
Mouse Swiss Prot No:Q9WU65
Immunogen:The antiserum was produced against synthesized peptide derived from human GK2. AA range:281-330
Specificity:GK2 Polyclonal Antibody detects endogenous levels of GK2 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:GK2;GKP2;GKTA;Glycerol kinase 2;GK 2;Glycerokinase 2;ATP:glycerol 3-phosphotransferase 2;Glycerol kinase; testis specific 2
Observed Band(KD):61kD
Background:catalytic activity:ATP + glycerol = ADP + sn-glycerol 3-phosphate.,function:Key enzyme in the regulation of glycerol uptake and metabolism.,pathway:Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.,similarity:Belongs to the FGGY kinase family.,subcellular location:In sperm the majority of the enzyme is bound to mitochondria.,
Function:catalytic activity:ATP + glycerol = ADP + sn-glycerol 3-phosphate.,function:Key enzyme in the regulation of glycerol uptake and metabolism.,pathway:Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.,similarity:Belongs to the FGGY kinase family.,subcellular location:In sperm the majority of the enzyme is bound to mitochondria.,
Subcellular Location:Mitochondrion outer membrane ; Single-pass type IV membrane protein . Cytoplasm . In sperm the majority of the enzyme is bound to mitochondria. .
Expression:Testis-specific (PubMed:33536340). Expressed in the midpiece of spermatozoa (PubMed:28852571).