Target：RM02

Fields：Ribosome

Gene Name：MRPL2 CGI-22

Protein Name：39S ribosomal protein L2, mitochondrial (L2mt) (MRP-L2)

Human Gene Id：51069

Human Swiss Prot No：Q5T653

Mouse Swiss Prot No：Q9D773

Rat Swiss Prot No：Q498T4

Immunogen：Synthesized peptide derived from human protein . at AA range: 210-290

Specificity：RM02 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：33kD

Background： Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL2 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 12q. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Function：similarity:Belongs to the ribosomal protein L2P family.,

Subcellular Location：Mitochondrion .

Expression： Ovary,Skin,