Target:RLA1
Fields:Ribosome;Coronavirus disease - COVID-19
Gene Name:RPLP1 RRP1
Protein Name:60S acidic ribosomal protein P1
Human Gene Id:6176
Human Swiss Prot No:P05386
Mouse Swiss Prot No:P47955
Rat Swiss Prot No:P19944
Immunogen:Synthesized peptide derived from human protein . at AA range: 30-110
Specificity:RLA1 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):12kD
Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P2. The P1 protein can interact with P0 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Two alternatively splic
Function:function:Plays an important role in the elongation step of protein synthesis.,similarity:Belongs to the ribosomal protein L12P family.,subunit:P1 and P2 exist as dimers at the large ribosomal subunit.,
Subcellular Location:cytoplasm,cytosol,ribosome,focal adhesion,cytosolic large ribosomal subunit,preribosome, large subunit precursor,extracellular exosome,
Expression: Epithelium,Eye,Hepatocyte,Pituitary,Placenta,Platelet,T-cel