Target:ANGP4
Fields:MAPK signaling pathway;Ras signaling pathway;Rap1 signaling pathway;HIF-1 signaling pathway;PI3K-Akt signaling pathway
Gene Name:ANGPT4 ANG3 ANG4
Protein Name:Angiopoietin-4 (ANG-4) (Angiopoietin-3) (ANG-3)
Human Gene Id:51378
Human Swiss Prot No:Q9Y264
Mouse Swiss Prot No:Q9WVH6
Immunogen:Synthesized peptide derived from human protein . at AA range: 150-230
Specificity:ANGP4 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):55kD
Background: Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The mechanism by which they contribute to angiogenesis is thought to involve regulation of endothelial cell interactions with supporting perivascular cells. The protein encoded by this gene functions as an agonist and is an angiopoietin. [provided by RefSeq, Jul 2008],
Function:caution:Was originally (PubMed:10218486) called angiopoietin-3.,function:Binds to tyrosine-protein kinase receptor TIE2 and activates it.,similarity:Contains 1 fibrinogen C-terminal domain.,tissue specificity:Highly expressed in the lung with much lower levels found in other tissues.,
Subcellular Location:Secreted .
Expression:Highly expressed in the lung with much lower levels found in other tissues.