Target：POLR3H

Fields：RNA polymerase;Cytosolic DNA-sensing pathway

Gene Name：POLR3H

Protein Name：DNA-directed RNA polymerase III subunit RPC8

Human Gene Id：171568

Human Swiss Prot No：Q9Y535

Mouse Gene Id：78929

Mouse Swiss Prot No：Q9D2C6

Immunogen：The antiserum was produced against synthesized peptide derived from human RPC8. AA range:151-200

Specificity：POLR3H Polyclonal Antibody detects endogenous levels of POLR3H protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：POLR3H;KIAA1665;RPC8;DNA-directed RNA polymerase III subunit RPC8;RNA polymerase III subunit C8;DNA-directed RNA polymerase III subunit H;RNA polymerase III subunit 22.9 kDa subunit;RPC22.9

Observed Band(KD)：23kD

Background：function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.,similarity:Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.,subunit:Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits (By similarity). Interacts with CRCP/RPC9. POLR3H/RPC8 and CRCP/RPC9 probably form a Pol III subcomplex.,

Function：function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.,similarity:Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.,subunit:Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits (By similarity). Interacts with CRCP/RPC9. POLR3H/RPC8 and CRCP/RPC9 probably form a Pol III subcomplex.,

Subcellular Location：Nucleus.

Expression： Adrenal gland,Brain,Pituitary,