Target:Podocan
Gene Name:PODN
Protein Name:Podocan
Human Gene Id:127435
Human Swiss Prot No:Q7Z5L7
Mouse Swiss Prot No:Q7TQ62
Immunogen:Synthesized peptide derived from the C-terminal region of human Podocan.
Specificity:Podocan Polyclonal Antibody detects endogenous levels of Podocan protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:PODN;SLRR5A;Podocan
Molecular Weight(Da):69kD
Background: The protein encoded by this gene is a member of the small leucine-rich repeat protein family and contains an amino terminal CX3CXCX7C cysteine-rich cluster followed by a leucine-rich repeat domain. Studies suggest that this protein could function to inhibit smooth muscle cell proliferation and migration following arterial injury. [provided by RefSeq, Jul 2016],
Function:PTM:N-glycosylated.,similarity:Belongs to the small leucine-rich proteoglycan (SLRP) family. Class V subfamily.,similarity:Contains 20 LRR (leucine-rich) repeats.,subunit:Binds to type I collagen.,tissue specificity:Kidney, heart, liver, pancreas and vascular smooth muscle cells.,
Subcellular Location:[Isoform 1]: Secreted, extracellular space, extracellular matrix.; [Isoform 2]: Cytoplasm .; [Isoform 3]: Cytoplasm .; [Isoform 4]: Cytoplasm .
Expression:Kidney, heart, liver, pancreas and vascular smooth muscle cells. Also detected in aortic intima (at protein level).